My main research interest is in developing computerized image analysis for medical applications. I have been working in that field since my Master Thesis work in 1973-74. That work was dealing with Analysis of cell images using video and computer technology. My doctoral thesis in 1977 was dealing with the same subject. I have since then supervised 15 doctoral theses in that field. My most recently supervised PhD Patrik Malm worked on developing computerized analysis of PAP-smears for early detection of cervical cancer, the same problem as I was addressing in my PhD thesis some 40 years ago. My early research resulted in a working, but far from cost-effective, solution. Since then commercial systems have appeared on the market but they are also very expensive and only used in rich countries. This time we are trying to develop a new generation system, cost effective enough to be used also in countries such as India where we have close collaboration.
Most of the previous work has been related to cancer research but now we are also turning into modern cell biology problems. Digital imaging cytometry is a field of rapidly growing importance. One of my former PhD students, Carolina Wählby, is now professor of Quantitative Microscopy and is very successfully leading this research in close collaboration with the Science for Life Laboratory project.
But cell image analysis is not my only interest. I also work with other medical images e.g. from radiology (CT, MR) or nuclear medicine (PET, SPECT). One of our main early results in that field was the development of a computerized brain atlas. Currently we have an exciting project on using haptic interaction to supplement the visual one in exploring medical images in particular for planning of maxillofacial surgery. We also have collaboration with Örjan Smedby at KTH on whole body angiographic images.
Our research at CBA also covers many other things. The first full professor in image analysis at the centre, starting 1993, was Gunilla Borgefors. She is well established in the field of digital geometry where she has made several fundamental contributions. Those methods are used in many of our applied projects both by her students and mine. A couple of her former students, Robin Strand and Filip Malmberg are working in close collaboration with the Radiology Department at Uppsala University developing fundamental medical image analysis algorithms.
A completely non-medical application area is our project on reading old handwritten documents headed by Anders Brun. We also have research on computer graphics and visualisation at Uppsala University with Stefan Seipel and Anders Hast. The current head of CBA, professor Ingela Nyström is also mainly working on visualization and interaction problems.
For a much more complete account of our research I refer to the other web-pages at www.cb.uu.se e.g. the personal web-pages of my colleagues and students and in particular to our annual report which lists all our current projects, publications, collaboration partners and other recent activities.