||Cell images with blobs are commonly seen in many biological research areas. Localizing these blobs, local maximas, can sometimes be fairly straight forward and in other cases not. All of my three ongoing projects have similar images containing cells and blobs, but possesses different problems in localizing these blobs. A method called Stable Wave Detector (SWD) is being tested and evaluated to solve the problem of finding the center position of blobs in these 3D images. Preliminary results show promising outcome of the SWD method but the need for reduction of parameter and increase in robustness is something that must be considered before the method can be used.