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Presentation Information     2013-03-11 (14:15)   •  The seminar room at Vi2

Speaker Omer Ishaq
Title Image-based Screening of Zebrafish
Abstract Quantitative microscopy has emerged as one of the most powerful tools for cell-based screening and whole-organism based assays, both in 2D and 3D. Zebrafish (Danio rerio) is an important vertebrate model organism in biomedical research thanks to its ease of handling and translucent body, enabling in vivo imaging. Zebrafish undergo spinal deformation upon exposure to chemical agents that inhibit DNA repair. We propose an automated, accurate and robust method for high-throughput measurement of fish embryo tail deformations from images of multi-fish micro-plate wells.