||Imaging based experiments are increasingly being used in systems
biology. This is in part due to the emergence of new technologies, such
as lab-on-a-chip microfluidics, which enable the type of dynamic
high-throughput experiments that systems biology requires. The studies
are often done with model organisms, such as the yeast Saccharomyces
cerevisiae, for which genome-wide knock-out experiments can be readily
made. Moreover, often a wide range of chemical environments need to be
tested with a high resolution. All this results in that the amount of
images that need to be analyzed can be almost overwhelming.
Several image analysis efforts that illustrate these points are
discussed in the presentation. In addition, microfluidic systems in
which both the experiment control and imaging are automated and
controlled based on image analysis results are discussed.